Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS

Ferroptosis is a form of lipid peroxidation-mediated cell death and damage triggered by excess iron and insufficiency in the glutathione antioxidant pathway. Oxidative stress is thought to play a crucial role in progressive forms of multiple sclerosis (MS) in which iron deposition occurs. In this st...

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Detalles Bibliográficos
Autores principales: Jhelum, Priya, Zandee, Stephanie, Ryan, Fari, Zarruk, Juan G., Michalke, Bernhard, Venkataramani, Vivek, Curran, Laura, Klement, Wendy, Prat, Alexandre, David, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369714/
https://www.ncbi.nlm.nih.gov/pubmed/37491291
http://dx.doi.org/10.1186/s40478-023-01617-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369714/
https://www.ncbi.nlm.nih.gov/pubmed/37491291
http://dx.doi.org/10.1186/s40478-023-01617-7

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