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Darier’s disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour

BACKGROUND: Darier’s disease (DD) is a genodermatosis caused by mutations of the ATP2A2 gene leading to disrupted keratinocyte adhesion. Recurrent episodes of skin inflammation and infections with a typical malodour in DD indicate a role for microbial dysbiosis. Here, for the first time, we investig...

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Detalles Bibliográficos
Autores principales: Amar, Yacine, Rogner, Danielle, Silva, Rafaela L., Foesel, Bärbel U., Ud-Dean, Minhaz, Lagkouvardos, Ilias, Steimle-Grauer, Susanne A., Niedermeier, Sebastian, Kublik, Susanne, Jargosch, Manja, Heinig, Matthias, Thomas, Jenny, Eyerich, Stefanie, Wikström, Jakob D., Schloter, Michael, Eyerich, Kilian, Biedermann, Tilo, Köberle, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369845/
https://www.ncbi.nlm.nih.gov/pubmed/37496039
http://dx.doi.org/10.1186/s40168-023-01587-x