Cargando…

Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes using Mellon

Cell-state density characterizes the distribution of cells along phenotypic landscapes and is crucial for unraveling the mechanisms that drive cellular differentiation, regeneration, and disease. Here, we present Mellon, a novel computational algorithm for high-resolution estimation of cell-state de...

Descripción completa

Detalles Bibliográficos
Autores principales: Otto, Dominik, Jordan, Cailin, Dury, Brennan, Dien, Christine, Setty, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369887/
https://www.ncbi.nlm.nih.gov/pubmed/37502954
http://dx.doi.org/10.1101/2023.07.09.548272