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Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes using Mellon
Cell-state density characterizes the distribution of cells along phenotypic landscapes and is crucial for unraveling the mechanisms that drive cellular differentiation, regeneration, and disease. Here, we present Mellon, a novel computational algorithm for high-resolution estimation of cell-state de...
Autores principales: | Otto, Dominik, Jordan, Cailin, Dury, Brennan, Dien, Christine, Setty, Manu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369887/ https://www.ncbi.nlm.nih.gov/pubmed/37502954 http://dx.doi.org/10.1101/2023.07.09.548272 |
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