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Microengineering 3D Collagen Matrices with Tumor-Mimetic Gradients in Fiber Alignment

In the tumor microenvironment (TME), collagen fibers facilitate tumor cell migration through the extracellular matrix. Previous studies have focused on studying the responses of cells on uniformly aligned or randomly aligned collagen fibers. However, the in vivo environment also features spatial gra...

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Detalles Bibliográficos
Autores principales: Joshi, Indranil M., Mansouri, Mehran, Ahmed, Adeel, Simon, Richard A., Bambizi, Poorya Esmaili, Desa, Danielle E., Elias, Tresa M., Brown, Edward B., Abhyankar, Vinay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369918/
https://www.ncbi.nlm.nih.gov/pubmed/37502844
http://dx.doi.org/10.1101/2023.07.09.548253