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Microengineering 3D Collagen Matrices with Tumor-Mimetic Gradients in Fiber Alignment
In the tumor microenvironment (TME), collagen fibers facilitate tumor cell migration through the extracellular matrix. Previous studies have focused on studying the responses of cells on uniformly aligned or randomly aligned collagen fibers. However, the in vivo environment also features spatial gra...
Autores principales: | Joshi, Indranil M., Mansouri, Mehran, Ahmed, Adeel, Simon, Richard A., Bambizi, Poorya Esmaili, Desa, Danielle E., Elias, Tresa M., Brown, Edward B., Abhyankar, Vinay V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369918/ https://www.ncbi.nlm.nih.gov/pubmed/37502844 http://dx.doi.org/10.1101/2023.07.09.548253 |
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