In vitro study to identify ligand‐independent function of estrogen receptor‐α in suppressing DNA damage‐induced chondrocyte senescence

In osteoarthritis (OA), chondrocytes undergo many pathological alternations that are linked with cellular senescence. However, the exact pathways that lead to the generation of a senescence‐like phenotype in OA chondrocytes are not clear. Previously, we found that loss of estrogen receptor‐α (ERα) w...

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Detalles Bibliográficos
Autores principales: Zhang, Xiurui, Xiang, Shiqi, Zhang, Yiqian, Liu, Silvia, Lei, Guanghua, Hines, Sophie, Wang, Ning, Lin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369926/
https://www.ncbi.nlm.nih.gov/pubmed/36622202
http://dx.doi.org/10.1096/fj.202201228R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369926/
https://www.ncbi.nlm.nih.gov/pubmed/36622202
http://dx.doi.org/10.1096/fj.202201228R

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