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Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport

Mitochondria transport is crucial for mitochondria distribution in axons and is mediated by kinesin-1-based anterograde and dynein-based retrograde motor complexes. While Miro and Milton/TRAK were identified as key adaptors between mitochondria and kinesin-1, recent studies suggest the presence of a...

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Detalles Bibliográficos
Autores principales: Wu, Youjun, Ding, Chen, Weinreb, Alexis, Manning, Laura, Swaim, Grace, Yogev, Shaul, Colón-Ramos, Daniel A., Hammarlund, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369933/
https://www.ncbi.nlm.nih.gov/pubmed/37502914
http://dx.doi.org/10.1101/2023.07.12.548706