Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues

PURPOSE: Lipid nanoparticles (LNPs) show promise in their ability to introduce mRNA to drive protein expression in specific cell types of the mammalian eye. Here, we examined the ability of mRNA encapsulated in lipid nanoparticles (LNPs) with two distinct formulations to drive gene expression in mou...

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Detalles Bibliográficos
Autores principales: Chambers, Cheri Z., Soo, Gillian L., Engel, Abbi L., Glass, Ian A., Frassetto, Andrea, Martini, Paolo G. V., Cherry, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369938/
https://www.ncbi.nlm.nih.gov/pubmed/37502987
http://dx.doi.org/10.1101/2023.07.13.548758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369938/
https://www.ncbi.nlm.nih.gov/pubmed/37502987
http://dx.doi.org/10.1101/2023.07.13.548758

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