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Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues
PURPOSE: Lipid nanoparticles (LNPs) show promise in their ability to introduce mRNA to drive protein expression in specific cell types of the mammalian eye. Here, we examined the ability of mRNA encapsulated in lipid nanoparticles (LNPs) with two distinct formulations to drive gene expression in mou...
Autores principales: | Chambers, Cheri Z., Soo, Gillian L., Engel, Abbi L., Glass, Ian A., Frassetto, Andrea, Martini, Paolo G. V., Cherry, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369938/ https://www.ncbi.nlm.nih.gov/pubmed/37502987 http://dx.doi.org/10.1101/2023.07.13.548758 |
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