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ScreenDMT reveals linoleic acid diols replicably associate with BMI and stimulate adipocyte calcium fluxes

Activating brown adipose tissue (BAT) improves systemic metabolism, making it a promising target for metabolic syndrome. BAT is activated by 12, 13-dihydroxy-9Z-octadecenoic acid (12, 13-diHOME), which we previously identified to be inversely associated with BMI and which directly improves metabolis...

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Detalles Bibliográficos
Autores principales: Dreyfuss, Jonathan M., Djordjilovic, Vera, Pan, Hui, Bussberg, Valerie, MacDonald, Allison M., Narain, Niven R., Kiebish, Michael A., Blüher, Matthias, Tseng, Yu-Hua, Lynes, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369939/
https://www.ncbi.nlm.nih.gov/pubmed/37503007
http://dx.doi.org/10.1101/2023.07.12.548737