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A microfluidic strategy to capture antigen-specific high affinity B cells

Assessing B cell affinity to pathogen-specific antigens prior to or following exposure could facilitate the assessment of immune status. Current standard tools to assess antigen-specific B cell responses focus on equilibrium binding of the secreted antibody in serum. These methods are costly, time-c...

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Detalles Bibliográficos
Autores principales: Alhassan, Ahmed M., Shirure, Venktesh S., Luo, Jean, Nguyen, Bryan B., Rollins, Zachary A., Shergill, Bhupinder S., Zhu, Xiangdong, Baumgarth, Nicole, George, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369944/
https://www.ncbi.nlm.nih.gov/pubmed/37503139
http://dx.doi.org/10.1101/2023.07.12.548739