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Prostaglandins as Candidate Ligands for a Per-ARNT-Sim (PAS) Domain of Steroid Receptor Coactivator 1 (SRC1)

Steroid receptor coactivators (SRCs) comprise a family of three paralogous proteins commonly recruited by eukaryotic transcription factors. Each SRC harbors two tandem Per-ARNT-Sim (PAS) domains that are broadly distributed that bind small molecules and regulate interactions. Using computational doc...

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Detalles Bibliográficos
Autores principales: Daffern, Nicolas, Kelley, Kade, Villegas, José A., Radhakrishnan, Ishwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369948/
https://www.ncbi.nlm.nih.gov/pubmed/37502902
http://dx.doi.org/10.1101/2023.07.13.548854