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Amyloid β accelerates age-related proteome-wide protein insolubility.
Loss of proteostasis is a highly conserved feature of aging across model organisms and typically results in the accumulation of insoluble protein aggregates. Protein insolubility is a central feature of major age-related neurodegenerative diseases including Alzheimer’s Disease (AD), where hundreds o...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369951/ https://www.ncbi.nlm.nih.gov/pubmed/37503138 http://dx.doi.org/10.1101/2023.07.13.548937 |