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DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization
BACKGROUND: Proper nuclear organization is critical for cardiomyocyte (CM) function, as global structural remodeling of nuclear morphology and chromatin structure underpins the development and progression of cardiovascular disease. Previous reports have implicated a role for DNA damage in cardiac hy...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370003/ https://www.ncbi.nlm.nih.gov/pubmed/37503243 http://dx.doi.org/10.1101/2023.07.14.549060 |