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DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization

BACKGROUND: Proper nuclear organization is critical for cardiomyocyte (CM) function, as global structural remodeling of nuclear morphology and chromatin structure underpins the development and progression of cardiovascular disease. Previous reports have implicated a role for DNA damage in cardiac hy...

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Detalles Bibliográficos
Autores principales: Stanczyk, Paulina, Tatekoshi, Yuki, Shapiro, Jason S., Nayudu, Krithika, Chen, Yihan, Zilber, Zachary, Schipma, Matthew, De Jesus, Adam, Mahmoodzadeh, Amir, Akrami, Ashley, Chang, Hsiang-Chun, Ardehali, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370003/
https://www.ncbi.nlm.nih.gov/pubmed/37503243
http://dx.doi.org/10.1101/2023.07.14.549060

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