Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

The role of morphogenetic forces in cell fate specification is an area of intense interest. Our prior studies suggested that the development of high cell-cell tension in human embryonic stem cells (hESC) colonies permits the Src-mediated phosphorylation of junctional β-catenin that accelerates its r...

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Detalles Bibliográficos
Autores principales: Ayad, Nadia M.E., Lakins, Johnathon N., Ghagre, Ajinkya, Ehrlicher, Allen J., Weaver, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
https://www.ncbi.nlm.nih.gov/pubmed/37503095
http://dx.doi.org/10.1101/2023.07.14.549074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
https://www.ncbi.nlm.nih.gov/pubmed/37503095
http://dx.doi.org/10.1101/2023.07.14.549074

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