Cargando…
Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
The role of morphogenetic forces in cell fate specification is an area of intense interest. Our prior studies suggested that the development of high cell-cell tension in human embryonic stem cells (hESC) colonies permits the Src-mediated phosphorylation of junctional β-catenin that accelerates its r...
Autores principales: | Ayad, Nadia M.E., Lakins, Johnathon N., Ghagre, Ajinkya, Ehrlicher, Allen J., Weaver, Valerie M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370032/ https://www.ncbi.nlm.nih.gov/pubmed/37503095 http://dx.doi.org/10.1101/2023.07.14.549074 |
Ejemplares similares
-
Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation
por: Srivastava, Luv Kishore, et al.
Publicado: (2021) -
Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
por: Drain, Allison P., et al.
Publicado: (2021) -
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells
por: Skelton, Rhys J.P., et al.
Publicado: (2016) -
Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells
por: Sladeček, Stanislava, et al.
Publicado: (2022) -
Mechanical Tension Drives Elongational Growth of the Embryonic Gut
por: Chevalier, Nicolas R., et al.
Publicado: (2018)