Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes

Common variants associated with schizophrenia are concentrated in non-coding regulatory sequences, but their precise target genes are context-dependent and impacted by cell-type-specific three-dimensional spatial chromatin organization. Here, we map long-range chromosomal conformations in isogenic h...

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Detalles Bibliográficos
Autores principales: Powell, Samuel K., Liao, Will, O’Shea, Callan, Kammourh, Sarah, Ghorbani, Sadaf, Rigat, Raymond, Elahi, Rahat, Deans, PJ Michael, Le, Derek J., Agarwal, Poonam, Seow, Wei Qiang, Wang, Kevin C., Akbarian, Schahram, Brennand, Kristen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370055/
https://www.ncbi.nlm.nih.gov/pubmed/37502907
http://dx.doi.org/10.1101/2023.07.17.549339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370055/
https://www.ncbi.nlm.nih.gov/pubmed/37502907
http://dx.doi.org/10.1101/2023.07.17.549339

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