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Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes
Common variants associated with schizophrenia are concentrated in non-coding regulatory sequences, but their precise target genes are context-dependent and impacted by cell-type-specific three-dimensional spatial chromatin organization. Here, we map long-range chromosomal conformations in isogenic h...
Autores principales: | Powell, Samuel K., Liao, Will, O’Shea, Callan, Kammourh, Sarah, Ghorbani, Sadaf, Rigat, Raymond, Elahi, Rahat, Deans, PJ Michael, Le, Derek J., Agarwal, Poonam, Seow, Wei Qiang, Wang, Kevin C., Akbarian, Schahram, Brennand, Kristen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370055/ https://www.ncbi.nlm.nih.gov/pubmed/37502907 http://dx.doi.org/10.1101/2023.07.17.549339 |
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