Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions

Degenerative diseases of the outer retina, including age-related macular degeneration (AMD), are characterized by atrophy of photoreceptors and retinal pigment epithelium (RPE). In these blinding diseases, macrophages are known to accumulate ectopically at sites of atrophy, but their ontogeny and fu...

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Detalles Bibliográficos
Autores principales: Yu, Chen, Lad, Eleonora M, Mathew, Rose, Littleton, Sejiro, Chen, Yun, Schlepckow, Kai, Degan, Simone, Chew, Lindsey, Amason, Joshua, Kalnitsky, Joan, Rickman, Catherine Bowes, Proia, Alan D, Colonna, Marco, Haass, Christian, Saban, Daniel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370087/
https://www.ncbi.nlm.nih.gov/pubmed/37502831
http://dx.doi.org/10.1101/2023.07.19.549403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370087/
https://www.ncbi.nlm.nih.gov/pubmed/37502831
http://dx.doi.org/10.1101/2023.07.19.549403

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