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C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types

INTRODUCTION: A hexanucleotide repeat expansion (HRE) intronic to chromosome 9 open reading frame 72 (C9orf72) is recognized as the most common genetic cause of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and ALS-FTD. Identifying genes that show similar regional co-expression...

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Detalles Bibliográficos
Autores principales: Broce, Iris J., Sirkis, Daniel W., Nillo, Ryan M., Bonham, Luke W., Lee, Suzee E., Miller, Bruce, Castruita, Patricia, Sturm, Virginia E., Sugrue, Leo S., Desikan, Rahul S., Yokoyama, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370095/
https://www.ncbi.nlm.nih.gov/pubmed/37503230
http://dx.doi.org/10.1101/2023.07.17.549377