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Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth
AML is a heterogenous disease caused by different mutations. We have previously shown that each mutational sub-type develops its specific gene regulatory network (GRN) with transcription factors interacting with multiple gene modules, many of which are transcription factor genes themselves. Here we...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370108/ https://www.ncbi.nlm.nih.gov/pubmed/37503022 http://dx.doi.org/10.1101/2023.07.18.549495 |