Deciphering Phage-Host Specificity Based on the Association of Phage Depolymerases and Bacterial Surface Glycan with Deep Learning

Phage tailspike proteins are depolymerases that target diverse bacterial surface glycans with high specificity, determining the host-specificity of numerous phages. To address the challenge of identifying tailspike proteins due to their sequence diversity, we developed SpikeHunter, an approach based...

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Detalles Bibliográficos
Autores principales: Yang, Yiyan, Dufault-Thompson, Keith, Yan, Wei, Cai, Tian, Xie, Lei, Jiang, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370184/
https://www.ncbi.nlm.nih.gov/pubmed/37503040
http://dx.doi.org/10.1101/2023.06.16.545366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370184/
https://www.ncbi.nlm.nih.gov/pubmed/37503040
http://dx.doi.org/10.1101/2023.06.16.545366

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