POTENT AND SELECTIVE A2AR MONOCLONAL ANTIBODY ANTAGONIST FOR THE TREATMENT OF CANCER

BACKGROUND AND SIGNIFICANCE: The presence of adenosine at abnormally high concentrations in tumor microenvironment leads to the activation of adenosine receptor 2A (A2aR) and represents one of the mechanisms for cancer patients to be resistance to immune checkpoint blockade therapies. CD39 and CD73...

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Detalles Bibliográficos
Autores principales: Hu, Changyun, Wang, Yanyan, Lan, Xiqian, Zhang, Jiandong, Zhao, Xinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370442/
http://dx.doi.org/10.1093/abt/tbad014.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370442/
http://dx.doi.org/10.1093/abt/tbad014.010

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