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APPLICATION OF EXCHABODY TECHNOLOGY FOR PAIRING VHHS TO ACHIEVE SYNERGISTIC EFFECTS

OBJECTIVE: Single-domain antibodies, such as VHH and nanobody, have shown potential for use in therapy and diagnostics. One application of VHHs is the tethering of two fragments to different epitopes on the same target, which is difficult to achieve with conventional antibodies. Synergistic heterolo...

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Detalles Bibliográficos
Autores principales: Luo, Yi, Zhan, Xiaoxiao, Shen, Yilong, Sheng, Ziyang, Zhu, Yin, Huang, Mingyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370449/
http://dx.doi.org/10.1093/abt/tbad014.025