High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele

For over 10,000 years, Andeans have resided at high altitude where the partial pressure of oxygen challenges human survival. Recent studies have provided evidence for positive selection acting in Andeans on the HIF2A (also known as EPAS1) locus, which encodes for a central transcription factor of th...

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Detalles Bibliográficos
Autores principales: Jorgensen, Kelsey, Song, Daisheng, Weinstein, Julien, Garcia, Obed A, Pearson, Laurel N, Inclán, María, Rivera-Chira, Maria, León-Velarde, Fabiola, Kiyamu, Melisa, Brutsaert, Tom D, Bigham, Abigail W, Lee, Frank S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370452/
https://www.ncbi.nlm.nih.gov/pubmed/37463421
http://dx.doi.org/10.1093/molbev/msad162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370452/
https://www.ncbi.nlm.nih.gov/pubmed/37463421
http://dx.doi.org/10.1093/molbev/msad162

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