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Enantioselective synthesis of hydantoins by chiral acid-catalysed condensation of glyoxals and ureas
Hydantoins are important scaffolds in natural products and pharmaceuticals, with only a few synthetic strategies available for their asymmetric preparation. We herein describe a single-step enantioselective synthesis of 5-monosubstituted hydantoins via condensation of glyoxals and ureas in the prese...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370572/ https://www.ncbi.nlm.nih.gov/pubmed/37502327 http://dx.doi.org/10.1039/d3sc01656k |