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The proximity-enabled sulfur fluoride exchange reaction in the protein context

The proximity-enabled sulfur(vi) fluoride exchange (SuFEx) reaction generates specific covalent linkages between proteins in cells and in vivo, which opens innovative avenues for studying elusive protein–protein interactions and developing potent covalent protein drugs. To exploit the power and expa...

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Detalles Bibliográficos
Autores principales: Yu, Bingchen, Cao, Li, Li, Shanshan, Klauser, Paul C., Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370592/
https://www.ncbi.nlm.nih.gov/pubmed/37502323
http://dx.doi.org/10.1039/d3sc01921g