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Engineered vitamin E-tethered non-immunogenic facial lipopeptide for developing improved siRNA based combination therapy against metastatic breast cancer

RNA interference based therapeutic gene silencing is an emerging platform for managing highly metastatic breast cancer. Cytosolic delivery of functional siRNA remains the key obstacle for efficient RNAi therapy. To overcome the challenges of siRNA delivery, we have engineered a vitamin E-tethered, s...

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Detalles Bibliográficos
Autores principales: Mallick, Argha Mario, Biswas, Abhijit, Mishra, Sukumar, Jadhav, Sonali, Chakraborty, Kasturee, Tripathi, Archana, Mukherjee, Arnab, Roy, Rituparna Sinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370593/
https://www.ncbi.nlm.nih.gov/pubmed/37502330
http://dx.doi.org/10.1039/d3sc01071f