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Engineered vitamin E-tethered non-immunogenic facial lipopeptide for developing improved siRNA based combination therapy against metastatic breast cancer
RNA interference based therapeutic gene silencing is an emerging platform for managing highly metastatic breast cancer. Cytosolic delivery of functional siRNA remains the key obstacle for efficient RNAi therapy. To overcome the challenges of siRNA delivery, we have engineered a vitamin E-tethered, s...
Autores principales: | Mallick, Argha Mario, Biswas, Abhijit, Mishra, Sukumar, Jadhav, Sonali, Chakraborty, Kasturee, Tripathi, Archana, Mukherjee, Arnab, Roy, Rituparna Sinha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370593/ https://www.ncbi.nlm.nih.gov/pubmed/37502330 http://dx.doi.org/10.1039/d3sc01071f |
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