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Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA

Despite the prognostic value of arterial stiffness (AS) and pulsatile hemodynamics (PH) for cardiovascular morbidity and mortality, epigenetic modifications that contribute to AS/PH remain unknown. To gain a better understanding of the link between epigenetics (DNA methylation) and AS/PH, we examine...

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Detalles Bibliográficos
Autores principales: Manichaikul, Ani, Hu, Xiaowei, Logan, Jeongok, Kwon, Younghoon, Lima, Joao, Jacobs, David, Duprez, Daniel, Brumback, Lyndia, Taylor, Kent, Durda, Peter, Johnson, Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell, Blackwell, Thomas, Papanicolaou, George, Mitchell, Gary, Rich, Stephen, Rotter, Jerome, Van Den Berg, David, Chirinos, Julio, Hughes, Timothy, Garrett-Bakelman, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371087/
https://www.ncbi.nlm.nih.gov/pubmed/37502922
http://dx.doi.org/10.21203/rs.3.rs-3125948/v1