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Dedicated bacterial esterases reverse lipopolysaccharide ubiquitylation to block immune sensing

Pathogenic bacteria have evolved diverse mechanisms to counteract cell-autonomous immunity, which otherwise guards both immune and non-immune cells from the onset of an infection(1,2). The versatile immunity protein Ring finger protein 213 (RNF213)(3–6) mediates the non-canonical ester-linked ubiqui...

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Detalles Bibliográficos
Autores principales: Szczesna, Magdalena, Huang, Yizhou, Lacoursiere, Rachel E., Bonini, Francesca, Pol, Vito, Koc, Fulya, Ward, Beatrice, Geurink, Paul P., Pruneda, Jonathan N., Thurston, Teresa L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371091/
https://www.ncbi.nlm.nih.gov/pubmed/37503018
http://dx.doi.org/10.21203/rs.3.rs-2986327/v1