Glucocorticoid stress hormones stimulate vesicle-free Tau secretion and spreading in the brain

Chronic stress and elevated levels of glucocorticoids (GCs), the main stress hormones, accelerate Alzheimer’s disease (AD) onset and progression. A major driver of AD progression is the spreading of pathogenic Tau protein between brain regions, precipitated by neuronal Tau secretion. While stress an...

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Detalles Bibliográficos
Autores principales: Waites, Clarissa, Yu, Qing, Du, Fang, Belli, Irla, Gomes, Patrícia, Sotiropoulos, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371092/
https://www.ncbi.nlm.nih.gov/pubmed/37503224
http://dx.doi.org/10.21203/rs.3.rs-3097174/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371092/
https://www.ncbi.nlm.nih.gov/pubmed/37503224
http://dx.doi.org/10.21203/rs.3.rs-3097174/v1

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