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The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anticholinesterases

Because of their potential to cause serious adverse health effects, significant efforts have been made to develop antidotes for organophosphate (OP) anti-cholinesterases, such as nerve agents. To be optimally effective, antidotes must not only reactivate inhibited target enzymes, but also have the a...

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Detalles Bibliográficos
Autores principales: Habiballah, Sohaib, Chambers, Janice, Meek, Edward, Reisfeld, Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371142/
https://www.ncbi.nlm.nih.gov/pubmed/37502931
http://dx.doi.org/10.21203/rs.3.rs-3163943/v1