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Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI

Regeneration in the injured spinal cord is limited by physical and chemical barriers. Acute implantation of a multichannel poly(lactide-co-glycolide) (PLG) bridge mechanically stabilizes the injury, modulates inflammation, and provides a permissive environment for rapid cellularization and robust ax...

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Detalles Bibliográficos
Autores principales: Nekanti, Usha, Sakthivel, Pooja, Zahedi, Atena, Creasman, Dana A., Nishi, Rebecca A., Dumont, Courtney M., Piltti, Katja M., Guardamondo, Glenn L., Hernandez, Norbert, Chen, Xingyuan, Song, Hui, Lin, Xiaoxiao, Martinez, Joshua, On, Lillian, Lakatos, Anita, Pawar, Kiran, David, Brian T., Guo, Zhiling, Seidlits, Stephanie K., Xu, Xiangmin, Shea, Lonnie D., Cummings, Brian J., Anderson, Aileen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371146/
https://www.ncbi.nlm.nih.gov/pubmed/37502943
http://dx.doi.org/10.21203/rs.3.rs-3044426/v1