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Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane
Naltrexone (NTX), a homologue of the opiate antidote naloxone, is an orally active long-acting mu-opioid receptor (MOP) antagonist used in the treatment of opiate dependence. NTX is also found to relieve craving for alcohol and is one of the few FDA-approved drugs for alcohol use disorder (AUD). Rep...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371157/ https://www.ncbi.nlm.nih.gov/pubmed/37503185 http://dx.doi.org/10.21203/rs.3.rs-3091960/v1 |