Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade

While the nervous system has reciprocal interactions with both cancer and the immune system, little is known about the potential role of tumor associated nerves (TANs) in modulating anti-tumoral immunity. Moreover, while peri-neural invasion is a well establish poor prognostic factor across cancer t...

Descripción completa

Detalles Bibliográficos
Autores principales: Baruch, Erez N., Nagarajan, Priyadahrshini, Gleber-Netto, Frederico O., Rao, Xiayu, Xie, Tongxin, Akhter, Shamima, Adewale, Adebayo, Shajedul, Islam, Mattson, Brandi J, Ferrarotto, Renata, Wong, Michael K., Davies, Michael A, Jindal, Sonali, Basu, Sreyashi, Harwood, Catherine, Leigh, Irene, Ajami, Nadim, Futreal, Andrew, Castillo, Micah, Gunaratne, Preethi, Goepfert, Ryan P., Khushalani, Nikhil, Wang, Jing, Watowich, Stephanie, Calin, George A, Migden, Michael R., Vermeer, Paola, D’Silva, Nisha, Yaniv, Dan, Burks, Jared K, Gomez, Javier, Dougherty, Patrick M, Tsai, Kenneth Y., Allison, James P, Sharma, Padmanee, Wargo, Jennifer, Myers, Jeffrey N., Gross, Neil D., Amit, Moran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371163/
https://www.ncbi.nlm.nih.gov/pubmed/37503252
http://dx.doi.org/10.21203/rs.3.rs-3161761/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371163/
https://www.ncbi.nlm.nih.gov/pubmed/37503252
http://dx.doi.org/10.21203/rs.3.rs-3161761/v1

Ejemplares similares