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Mitochondrial Magnesium is the cationic rheostat for MCU-mediated mitochondrial Ca(2+) uptake

Calcium (Ca(2+)) uptake by mitochondria is essential in regulating bioenergetics, cell death, and cytosolic Ca(2+) transients. Mitochondrial Calcium Uniporter (MCU) mediates the mitochondrial Ca(2+) uptake. MCU is a heterooligomeric complex with a pore-forming component and accessory proteins requir...

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Detalles Bibliográficos
Autores principales: Ponnusamy, Thiruvelselvan, Velusamy, Prema, Kumar, Amrendra, Morris, Daniel, Zhang, Xueqian, Ning, Gang, Klinger, Marianne, Copper, Jean E., Rajan, Sudarsan, Cheung, Joseph Y, Natarajaseenivasan, Kalimuthusamy, Mnatsakanyan, Nelli, Shanmughapriya, Santhanam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371168/
https://www.ncbi.nlm.nih.gov/pubmed/37502932
http://dx.doi.org/10.21203/rs.3.rs-3088175/v1