Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum

Heart failure (HF) is a complex trait, influenced by environmental and genetic factors, that affects over 30 million individuals worldwide. Historically, the genetics of HF have been studied in Mendelian forms of disease, where rare genetic variants have been linked to familial cardiomyopathies. Mor...

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Detalles Bibliográficos
Autores principales: Lee, David S.M., Cardone, Katie M., Zhang, David Y., Abramowitz, Sarah, DePaolo, John S., Aragam, Krishna G., Biddinger, Kiran, Conery, Mitchell, Dilitikas, Ozan, Hoffman-Andrews, Lily, Judy, Renae L., Khan, Atlas, Kulo, Iftikhar, Puckelwartz, Megan J., Reza, Nosheen, Satterfield, Benjamin A., Singhal, Pankhuri, Arany, Zoltan P., Cappola, Thomas P., Carruth, Eric, Day, Sharlene M., Do, Ron, Haggarty, Christopher M., Joseph, Jacob, McNally, Elizabeth, Nadkarni, Girish, Owens, Anjali T., Rader, Daniel J., Ritchie, Marylyn D., Sun, Yan, Voight, Benjamin F., Levin, Michael G., Damrauer, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371173/
https://www.ncbi.nlm.nih.gov/pubmed/37503172
http://dx.doi.org/10.1101/2023.07.16.23292724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371173/
https://www.ncbi.nlm.nih.gov/pubmed/37503172
http://dx.doi.org/10.1101/2023.07.16.23292724

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