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Identification of flucloxacillin-modified hepatocellular proteins: implications in flucloxacillin-induced liver injury

Flucloxacillin is a β-lactam antibiotic associated with a high incidence of drug-induced liver injury. Although expression of HLA-B*57:01 is associated with increased susceptibility, little is known of the pathological mechanisms involved in the induction of the clinical phenotype. Irreversible prot...

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Detalles Bibliográficos
Autores principales: Ali, Serat-E, Waddington, James C, Lister, Adam, Sison-Young, Rowena, Jones, Robert P, Rehman, Adeeb H, Goldring, Chris E P, Naisbitt, Dean J, Meng, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371196/
https://www.ncbi.nlm.nih.gov/pubmed/36782357
http://dx.doi.org/10.1093/toxsci/kfad015