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Identification of flucloxacillin-modified hepatocellular proteins: implications in flucloxacillin-induced liver injury
Flucloxacillin is a β-lactam antibiotic associated with a high incidence of drug-induced liver injury. Although expression of HLA-B*57:01 is associated with increased susceptibility, little is known of the pathological mechanisms involved in the induction of the clinical phenotype. Irreversible prot...
Autores principales: | Ali, Serat-E, Waddington, James C, Lister, Adam, Sison-Young, Rowena, Jones, Robert P, Rehman, Adeeb H, Goldring, Chris E P, Naisbitt, Dean J, Meng, Xiaoli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371196/ https://www.ncbi.nlm.nih.gov/pubmed/36782357 http://dx.doi.org/10.1093/toxsci/kfad015 |
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