Searching for molecular hypoxia sensors among oxygen-dependent enzymes

The ability to sense and respond to changes in cellular oxygen levels is critical for aerobic organisms and requires a molecular oxygen sensor. The prototypical sensor is the oxygen-dependent enzyme PHD: hypoxia inhibits its ability to hydroxylate the transcription factor HIF, causing HIF to accumul...

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Detalles Bibliográficos
Autores principales: Li, Li, Shen, Susan, Bickler, Philip, Jacobson, Matthew P, Wu, Lani F, Altschuler, Steven J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371230/
https://www.ncbi.nlm.nih.gov/pubmed/37494095
http://dx.doi.org/10.7554/eLife.87705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371230/
https://www.ncbi.nlm.nih.gov/pubmed/37494095
http://dx.doi.org/10.7554/eLife.87705

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