H2Bub1 loss is an early contributor to clear cell ovarian cancer progression

Epigenetic aberrations, including posttranslational modifications of core histones, are major contributors to cancer. Here, we define the status of histone H2B monoubiquitylation (H2Bub1) in clear cell ovarian carcinoma (CCOC), low-grade serous carcinoma, and endometrioid carcinomas. We report that...

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Detalles Bibliográficos
Autores principales: Ferrari, Adam J., Rawat, Priyanka, Rendulich, Hannah S., Annapragada, Akshaya V., Kinose, Yasuto, Zhang, Xiaoming, Devins, Kyle, Budina, Anna, Scharpf, Robert B., Mitchell, Marilyn A., Tanyi, Janos L., Morgan, Mark A., Schwartz, Lauren E., Soong, T. Rinda, Velculescu, Victor E., Drapkin, Ronny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371241/
https://www.ncbi.nlm.nih.gov/pubmed/37345659
http://dx.doi.org/10.1172/jci.insight.164995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371241/
https://www.ncbi.nlm.nih.gov/pubmed/37345659
http://dx.doi.org/10.1172/jci.insight.164995

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