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CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis

ˆCCL24 is a pro-fibrotic, pro-inflammatory chemokine expressed in several chronic fibrotic diseases. In the liver, CCL24 plays a role in fibrosis and inflammation, and blocking CCL24 led to reduced liver injury in experimental models. We studied the role of CCL24 in primary sclerosing cholangitis (P...

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Detalles Bibliográficos
Autores principales: Greenman, Raanan, Segal-Salto, Michal, Barashi, Neta, Hay, Ophir, Katav, Avi, Levi, Omer, Vaknin, Ilan, Aricha, Revital, Aharoni, Sarit, Snir, Tom, Mishalian, Inbal, Olam, Devorah, Amer, Johnny, Salhab, Ahmad, Safadi, Rifaat, Maor, Yaakov, Trivedi, Palak, Weston, Christopher J., Saffioti, Francesca, Hall, Andrew, Pinzani, Massimo, Thorburn, Douglas, Peled, Amnon, Mor, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371243/
https://www.ncbi.nlm.nih.gov/pubmed/37345655
http://dx.doi.org/10.1172/jci.insight.162270