Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland

Defects in endoplasmic reticulum (ER) proteostasis have been linked to diseases in multiple organ systems. Here we examined the impact of perturbation of ER proteostasis in mice bearing thyrocyte-specific knockout of either HRD1 (to disable ER-associated protein degradation [ERAD]) or ATG7 (to disab...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaohan, Young, Crystal, Liao, Xiao-Hui, Refetoff, Samuel, Torres, Mauricio, Tomer, Yaron, Stefan-Lifshitz, Mihaela, Zhang, Hao, Larkin, Dennis, Fang, Deyu, Qi, Ling, Arvan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371246/
https://www.ncbi.nlm.nih.gov/pubmed/37345654
http://dx.doi.org/10.1172/jci.insight.169937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371246/
https://www.ncbi.nlm.nih.gov/pubmed/37345654
http://dx.doi.org/10.1172/jci.insight.169937

Ejemplares similares