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Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus–infected mice

Antiviral immunity often requires CD8(+) cytotoxic T lymphocytes (CTLs) that actively migrate and search for virus-infected targets. Regulatory T cells (Tregs) have been shown to suppress CTL responses, but it is not known whether this is also mediated by effects on CTL motility. Here, we used intra...

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Detalles Bibliográficos
Autores principales: Mittermüller, Daniela, Otto, Lucas, Long, Zoë, Kraus, Andreas, Beer, Alexander, Hasenberg, Anja, Zelinskyy, Gennadiy, Westmeier, Jaana, Hasenkrug, Kim J., Dittmer, Ulf, Gunzer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371334/
https://www.ncbi.nlm.nih.gov/pubmed/37427590
http://dx.doi.org/10.1172/jci.insight.167482