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Regulatory T cells suppress the motility of cytotoxic T cells in Friend retrovirus–infected mice
Antiviral immunity often requires CD8(+) cytotoxic T lymphocytes (CTLs) that actively migrate and search for virus-infected targets. Regulatory T cells (Tregs) have been shown to suppress CTL responses, but it is not known whether this is also mediated by effects on CTL motility. Here, we used intra...
Autores principales: | Mittermüller, Daniela, Otto, Lucas, Long, Zoë, Kraus, Andreas, Beer, Alexander, Hasenberg, Anja, Zelinskyy, Gennadiy, Westmeier, Jaana, Hasenkrug, Kim J., Dittmer, Ulf, Gunzer, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371334/ https://www.ncbi.nlm.nih.gov/pubmed/37427590 http://dx.doi.org/10.1172/jci.insight.167482 |
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