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ADCC-activating antibodies correlate with decreased risk of congenital human cytomegalovirus transmission

Human cytomegalovirus (HCMV) is the most common vertically transmitted infection worldwide, yet there are no vaccines or therapeutics to prevent congenital HCMV (cCMV) infection. Emerging evidence indicates that antibody Fc effector functions may be a previously underappreciated component of materna...

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Detalles Bibliográficos
Autores principales: Semmes, Eleanor C., Miller, Itzayana G., Rodgers, Nicole, Phan, Caroline T., Hurst, Jillian H., Walsh, Kyle M., Stanton, Richard J., Pollara, Justin, Permar, Sallie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371338/
https://www.ncbi.nlm.nih.gov/pubmed/37427588
http://dx.doi.org/10.1172/jci.insight.167768