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Modeling of ACE2 and antibodies bound to SARS-CoV-2 provides insights into infectivity and immune evasion

Given the COVID-19 pandemic, there is interest in understanding ligand-receptor features and targeted antibody-binding attributes against emerging SARS-CoV-2 variants. Here, we developed a large-scale structure-based pipeline for analysis of protein-protein interactions regulating SARS-CoV-2 immune...

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Detalles Bibliográficos
Autores principales: Lubin, Joseph H., Markosian, Christopher, Balamurugan, D., Ma, Minh T., Chen, Chih-Hsiung, Liu, Dongfang, Pasqualini, Renata, Arap, Wadih, Burley, Stephen K., Khare, Sagar D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371346/
https://www.ncbi.nlm.nih.gov/pubmed/37261904
http://dx.doi.org/10.1172/jci.insight.168296